CAS 4916-57-8: 1,2-Bis(4-pyridyl)ethane

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

1,2-Di(4-pyridyl)ethane is a fluorescent compound that emits light when irradiated with UV light. It has been shown to inhibit the production of nitric oxide in liver cells and to interact with DNA polymerase chains by forming hydrogen bonds with the complementary bases in the DNA molecule. The x-ray crystal structures of 1,2-di(4-pyridyl)ethane show how it binds to its complementary base pair, adenine. This binding causes a change in the coordination geometry of the nitrogen atoms at one end of the molecule and a shift in electron density from one side of the molecule to the other.

1,2-Bis(4-pyridyl)ethane

1,2-Bis-(4-pyridyl)ethane is a fine chemical that is a versatile building block in the synthesis of complex compounds. It has been used as a research chemical and reagent for the study of DNA and RNA synthesis. 1,2-Bis-(4-pyridyl)ethane is also an important intermediate for the synthesis of drugs such as cephalosporins, which are antibiotics used to treat bacterial infections. The compound has been shown to be effective in treating MRSA infections. 1,2-Bis-(4-pyridyl)ethane can also be used as a scaffold for the synthesis of other compounds.