Inosine, 5'-azido-2',5'-dideoxy- (CAS 496809-83-7) is a modified nucleoside that features an azido group at the 5' position and lacks hydroxyl groups at the 2' and 5' positions, which distinguishes it from standard ribonucleosides. This compound is characterized by its structural composition, which includes a purine base (inosine) linked to a sugar moiety that is modified to enhance its stability and alter its biological activity. The presence of the azido group introduces unique reactivity, making it useful in various biochemical applications, including as a potential antiviral agent or in nucleic acid research. The absence of hydroxyl groups contributes to its resistance to nucleolytic degradation, allowing for prolonged activity in biological systems. Inosine derivatives are often studied for their roles in cellular processes and their potential therapeutic applications, particularly in the context of nucleoside analogs that can interfere with viral replication or modulate immune responses.

Inosine, 5'-azido-2',5'-dideoxy-

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5'-Azido-2',5'-dideoxyinosine is a novel nucleoside which has been synthesized to investigate its anticancer and antiviral properties. 5'-Azido-2',5'-dideoxyinosine is an activator of ribonucleosides and deoxyribonucleosides, converting them into the corresponding monophosphate or diphosphate form. This product can be used as a building block for the synthesis of phosphoramidites and modified nucleosides. 5'-Azido-2',5'-dideoxyinosine has shown activity against cancer cells in vitro, in particular leukemia cell lines. It also has antiviral activity against HIV, herpes simplex virus type 1, and human cytomegalovirus (HCMV).

CAS 496809-83-7: Inosine, 5'-azido-2',5'-dideoxy-

5'-Azido-2',5'-dideoxyinosine

Ref: 3D-NA45439