CAS 499-81-0: 3,5-Pyridinedicarboxylic acid

Pyridine-3,5-dicarboxylic acid

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications Competitive inhibitor of butyrobetaine hydroxylase References Decristoforo, C., et al.: Nuc. Med. Biol., 26, 389 (1999), Rose, N., et al.: J. Med. Chem., 51, 7053 (2008),

3,5-Pyridinedicarboxylic acid (3,5-PDCA) is a molecule that belongs to the group of flavonol glycosides. It inhibits esterases and hydrolases by forming strong hydrogen bonding interactions with amino acid residues on their active sites. 3,5-PDCA also has been shown to inhibit the activity of several enzymes such as choline esterase and acetylcholinesterase. The enzyme inhibition properties have been demonstrated using FTIR spectroscopy. 3,5-PDCA has been found to be effective in the treatment of picolinic acid induced seizures in mice. This molecule can also form particle crystals with a particle size of about 0.1 μm. The thermal expansion coefficient of 3,5-PDCA is 2 x 10^-6 K^-1 while that of picolinic acid is 6 x 10^-6 K^-1

3,5-Pyridinedicarboxylic Acid is a useful organic compound for research related to life sciences. The catalog number is T66974 and the CAS number is 499-81-0.