CAS 50-04-4: Cortisone, 21-acetate

CORTISONE ACETATE CRS

Cortisone acetate

Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and

Cortisone acetate is a synthetic corticosteroid, which is a derivative of cortisone, a naturally occurring hormone produced by the adrenal cortex. As a pharmaceutical compound, cortisone acetate acts primarily as an anti-inflammatory and immunosuppressive agent. Its mode of action involves the conversion into cortisol, a glucocorticoid, which then interacts with glucocorticoid receptors to modulate the transcription of responsive genes. This process reduces the production of pro-inflammatory cytokines and inhibits the function of immune cells, thereby producing an anti-inflammatory effect. Cortisone acetate is utilized in clinical settings to treat a range of conditions characterized by inflammation and immune system hyperactivity. Common applications include the management of arthritis, allergies, and skin disorders, among other conditions where modulation of the body's inflammatory response is advantageous. Additionally, it is used in the treatment of adrenal insufficiency, where it compensates for the lack of endogenous corticosteroid production. By reducing inflammation and modifying immune responses, cortisone acetate plays a crucial role in the therapeutic management of several inflammatory and autoimmune conditions.

Cortisone acetate

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Adrenal cortical hormones and their derivatives nesoi

Cortisone acetate

Impurity Hydrocortisone Acetate EP Impurity D Applications Cortisone Acetate (Hydrocortisone Acetate EP Impurity D) is a glucocorticoid. Cortisone Acetate is an antiinflammatory agent. Cortisone Acetate is bioavailable and readily converted to the therapeutically active form, Hydrocotisone (H714615). References Colburn, W. et al.: J. Clin. Pharmacol., 20, 428 (1980); Bailey, J.M. et al.: Atherosclerosis, 17, 515 (1973);