The chemical substance known as Urea, N-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-N'-(3-methylphenyl)-, with the CAS number 501698-03-9, is a complex organic compound characterized by its urea functional group, which is central to its structure. This compound features a thieno[2,3-d]pyrimidine moiety, indicating a fused ring system that contributes to its biological activity and potential pharmacological properties. The presence of amino and phenyl groups suggests that it may engage in hydrogen bonding and π-π interactions, which can influence its solubility and reactivity. Typically, such compounds are of interest in medicinal chemistry due to their potential as therapeutic agents, particularly in targeting specific biological pathways. The molecular structure implies a degree of lipophilicity, which may affect its absorption and distribution in biological systems. Overall, this compound exemplifies the intricate relationship between molecular structure and biological function, making it a subject of interest for further research and development in drug discovery.

Urea,N-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-N'-(3-methylphenyl)-

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GDP366

1-(4-(4-Aminothieno[2,3-D]Pyrimidin-5-Yl)Phenyl)-3-(M-Tolyl)Urea

GDP366 is a recombinant protein that inhibits the growth of leukemia cells. It has been shown to inhibit the expression of survivin, which is an endogenous substance that protects cells from dying. The inhibition of survivin allows for apoptosis and cell death. This drug also has a low energy requirement and may be used in cancer patients with low energy levels.

GDP366,  induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.

CAS 501698-03-9: Urea,N-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-N'-(3-methylphenyl)-

GDP366

Ref: 54-BUP09323

GDP366

Ref: IN-DA01FPER

1-(4-(4-Aminothieno[2,3-D]Pyrimidin-5-Yl)Phenyl)-3-(M-Tolyl)Urea

Ref: 54-OR1022849

GDP366

Ref: 3D-BVA69803

GDP366

Ref: TM-T11383