CAS 50488-42-1: 2-Bromo-5-(trifluoromethyl)pyridine

2-Bromo-5-trifluoromethylpyridine is a hypervalent molecule that can be used to synthesize other compounds. It is an efficient means of producing diazonium salts, which are useful intermediates in organic synthesis. 2-Bromo-5-trifluoromethylpyridine reacts with alkyl halides and its radical species initiate the cross-coupling reaction. This reaction can take place in a wide range of solvents and with a variety of functional groups. The efficiency of this reaction depends on the nature of the halide, with fluorine being the most reactive. 2-Bromo-5-trifluoromethylpyridine cleaves bonds by attacking c-h bonds, which is why it is often used as a catalyst for bond cleavage reactions.

2-Bromo-5-(trifluoromethyl)pyridine is a substrate used in a palladium-catalyzed α-arylation of a Refomatsky reagent. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2-Bromo-5-(trifluoromethyl)pyridine