CAS 506-37-6: Nervonic Acid

Applications Nervonic acid is a fatty acid. It is particularly abundant in the white matter of animal brains and in peripheral nervous tissue where nervonyl sphingolipids are enriched in the myelin sheath of nerve fibers. It is one of the major fatty acids in brain sphingolipids, normally accounting for approximately 40% of the total fatty acids in sphingolipids. References Sandhir, R., et al.: J. Lipid Res., 39, 2161 (1998)

Nervonic acid, enriched in sphingomyelin, may boost brain function and combat demyelination; it's linked to lower obesity risks and altered levels in ALD.

Nervonic acid is a monounsaturated fatty acid, which is predominantly sourced from natural materials such as plant oils and animal tissues. It serves a critical role in the biosynthesis of nerve cell membranes and is particularly abundant in the white matter of the human brain. Its presence is essential for the formation and maintenance of myelin, the protective covering around nerves, due to its incorporation into sphingolipids, which are integral components of myelin. The mode of action of nervonic acid involves its participation in lipid metabolism and integration into neuronal membranes, which subsequently supports cellular signaling and nerve cell communication. Its influence extends to maintaining the integrity and functionality of neuronal cells, thus contributing to overall cognitive and neurological health. Nervonic acid is primarily utilized in research focusing on neurological health and disorders such as multiple sclerosis and other demyelinating conditions. It is investigated for its potential in enhancing cognitive functions and in the treatment of neural pathologies due to its essential role in myelin sheath biosynthesis and repair. As such, it is a valuable molecule in neuroscience research, particularly in the context of understanding and potentially mitigating neurological diseases.

Nervonic acid

Nervonic Acid