Acetyl iodide, with the chemical formula C2H3IO and CAS number 507-02-8, is an organic compound characterized by its reactivity and utility in organic synthesis. It appears as a colorless to pale yellow liquid with a pungent odor, indicative of its volatility and potential irritant properties. Acetyl iodide is known for its role as an acetylating agent, facilitating the introduction of acetyl groups into various substrates, which is valuable in the synthesis of esters, amides, and other derivatives. The compound is sensitive to moisture and can hydrolyze in the presence of water, producing acetic acid and hydroiodic acid. It is typically handled under anhydrous conditions to maintain its stability. Due to its iodine content, acetyl iodide can also participate in halogenation reactions. Safety precautions are essential when working with this compound, as it can be harmful if inhaled or absorbed through the skin. Proper storage in a cool, dry place, away from incompatible materials, is crucial to ensure safety and stability.

Acetyl iodide

Acetyl iodide is an organic chemical compound with the formula CH3COI. It is a colorless liquid and reacts with nucleophiles to form acyl halides. Acetyl iodide is used as a reagent in organic synthesis, primarily for acetylation and alkylation reactions. Magnetic resonance spectroscopy has been used to study the reaction products of acetyl iodide with water and other nucleophiles. The reaction mechanism of acetyl iodide involves nucleophilic attack on the carbonyl carbon atom, resulting in formation of an acyl chloride. Acetyl iodide is also commonly used as a dry weight measurement standard in biochemistry assays since it has a constant molecular weight of 74.05 g/mol.

CAS 507-02-8: Acetyl iodide

Acetyl iodide

Ref: 3D-AAA50702

Acetyl Iodide

Ref: 3B-A0095

Acetyl iodide

Ref: 54-OR938283