Phenelzine is a non-selective monoamine oxidase inhibitor (MAOI) primarily used as an antidepressant. It is characterized by its ability to increase the levels of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain, which can help alleviate symptoms of depression and anxiety. The chemical structure of phenelzine includes a hydrazine moiety, contributing to its pharmacological activity. It is typically administered in tablet form and is known for its potential side effects, including dietary restrictions due to interactions with tyramine-rich foods, which can lead to hypertensive crises. Phenelzine is also associated with other side effects such as dizziness, weight gain, and insomnia. Due to its mechanism of action, it is often prescribed when other antidepressants have failed or in cases of atypical depression. Patients on phenelzine require careful monitoring and guidance from healthcare providers to manage its effects and interactions effectively.

Phenelzine

51-71-8: (2-Phenylethyl)hydrazine, 1-(2-Phenethyl)hydrazine, 1-(2-Phenylethyl)hydrazine, 1-Hydrazino-2-phenylethane, 2-Phenylethylhydrazine, Fenelzina, Hydrazine, (2-phenylethyl)-, Hydrazine, phenethyl-, N-Phenethylhydrazine, Nardil, Phenalzine, Phenelzin, Phenethylhydrazine, Phenylethylhydrazine, Phenylzine, W 1544, β-Phenylethylhydrazine, Phenelzine

Phenelzine is a MAOI antidepressant, boosting brain catecholamines, effective for endogenous depression.

Hydrazine, (2-phenylethyl)-

2-Phenylethylhydrazine (2PEH) is an experimental drug that is reactive. It has been shown to have anti-inflammatory properties in a model system of inflammation in animals. 2PEH also inhibits the enzyme monoamine oxidase, which prevents the breakdown of serotonin, resulting in increased levels of this neurotransmitter. The use of 2PEH as a pharmacological treatment for atherosclerotic lesions may be due to its inhibitory properties on 5HT2 receptors and 2 adrenergic receptors. It has also been shown to induce neuronal death in animal studies.

CAS 51-71-8: Phenelzine

Phenelzine

Ref: TM-T9540

Hydrazine, (2-phenylethyl)-

Ref: IN-DA00I94Y

2-Phenylethylhydrazine

Ref: 3D-FP13942