5-Chloro-3-pyridinecarbonitrile is an organic compound characterized by its pyridine ring, which is a six-membered aromatic heterocycle containing one nitrogen atom. The presence of a cyano group (-C≡N) at the 3-position and a chlorine atom at the 5-position of the pyridine ring contributes to its chemical reactivity and properties. This compound typically appears as a solid at room temperature and is soluble in polar organic solvents. It is often used in the synthesis of pharmaceuticals and agrochemicals due to its ability to act as a building block in various chemical reactions. The presence of the cyano group enhances its utility in nucleophilic substitution reactions, while the chlorine atom can participate in electrophilic aromatic substitution. Additionally, 5-Chloro-3-pyridinecarbonitrile may exhibit biological activity, making it of interest in medicinal chemistry. As with many chemical substances, proper handling and safety precautions are essential due to potential toxicity and environmental impact.

5-Chloro-3-pyridinecarbonitrile

51269-82-0: 3-Pyridinecarbonitrile, 5-chloro-, 5-Chloro-3-cyanopyridine, 5-Chloro-3-pyridinecarbonitrile, 5-Chloro-Nicotinonitrile, 5-Chloronicotinonitrile

5-Chloro-3-cyanopyridine is a PPAR ligand that has shown to be a potent insulin secretagogue and glucose level regulator in animal models. This compound binds to the PPAR alpha, beta/delta, and gamma subtypes with high affinity and selectivity. 5-Chloro-3-cyanopyridine has been found to have a low molecular weight and tunable structure that may allow for optimization of the drug's pharmacological properties. The structural modification of 5-chloro-3-cyanopyridine may lead to improved pharmacokinetics, bioavailability, or metabolic stability. In addition, this compound has been shown to have cardiovascular activity as well as antihypertensive effects in animal studies.

CAS 51269-82-0: 5-Chloro-3-pyridinecarbonitrile

5-Chloro-3-cyanopyridine

Ref: 3D-FC155825

5-Chloro-3-Cyanopyridine

Ref: IN-DA00348Z

5-Chloronicotinonitrile

Ref: 54-OR46037

5-Chloronicotinonitrile

Ref: 10-F046518