CAS 518-28-5: Podophyllotoxin
Formula:C22H22O8
InChI:InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1
InChI key:InChIKey=YJGVMLPVUAXIQN-XVVDYKMHSA-N
SMILES:O=C1[C@@]2([C@@H](C=3C([C@H](O)[C@]2(CO1)[H])=CC4=C(C3)OCO4)C5=CC(OC)=C(OC)C(OC)=C5)[H]
Synonyms:- (5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo(3',4':6,7)naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
- (5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
- (5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
- (5R,5aS,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
- 1,3,3A,4,9,9A-Hexahidro-9-Hidroxi-6,7-(Metilenodioxi)-4-(3',4',5'-Trimetoxifenil)Benzo[F]Isobenzofuran-3-Ona
- 1,3,3A,4,9,9A-Hexahydro-9-Hydroxy-6,7-(Methylenedioxy)-4-(3',4',5'-Trimethoxyphenyl)Benz[F]Isobenzofuran-3-One
- 1,3,3A,4,9,9A-Hexahydro-9-Hydroxy-6,7-(Methylenedioxy)-4-(3',4',5'-Trimethoxyphenyl)Benzo[F]Isobenzofuranne-3-One
- 1,3,3a,4,9,9a-Hexahydro-9-hydroxy-6,7-(methylendioxy)-4-(3',4',5'-trimethoxyphenyl)benz[f]isobenzofuran-3-on
- 9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
- Condyline
- Condylox
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Found 17 products.
(5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
CAS:Formula:C22H22O8Purity:98%Color and Shape:SolidMolecular weight:414.4053Podofilox
CAS:Podofilox, a toxic spindle poison from Podophyllum roots, treats warts and keratoses, irritates skin, and may fight cancer.Formula:C22H22O8Purity:98% - 99.73%Color and Shape:Solvated Crystals SolidMolecular weight:414.41Podophyllotoxin
CAS:Controlled ProductStability Very Hygroscopic Applications Skin treatment for genital warts caused by some types of HPVs. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Kelly, M.G. & Hartwell, J.L.; J. of the Nat'l Cancer Inst., 14, 967 (1954), Gupta, R.S.; Somatic Cell Genetics, 7, 59 (1981), Gupta, R.S.; Cancer Research, 43, 505 (1983a)Formula:C22H22O8Color and Shape:White To Off-WhiteMolecular weight:414.41Podophyllotoxin-d6
CAS:Formula:C22H16D6O8Color and Shape:White To Off-White SolidMolecular weight:420.45Podophyllotoxin
CAS:Formula:C22H22O8Purity:>95.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:414.41(-)-Podophyllotoxin
CAS:(-)-Podophyllotoxin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C22H22O8Purity:(HPLC) ≥99%Color and Shape:PowderMolecular weight:414.42Podophyllotoxin, 95%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C22H22O8Purity:95%Color and Shape:White to off-white, PowderMolecular weight:414.41Podophyllotoxin
CAS:LactoneFormula:C22H22O8Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:414.41Podophyllotoxin
CAS:Podophyllotoxin is a potent antimitotic agent, which is derived from the roots and rhizomes of plants belonging to the genus Podophyllum, such as Podophyllum peltatum and Podophyllum emodi. Its mode of action involves the inhibition of microtubule assembly, leading to the disruption of mitotic spindle formation during cell division. This results in the arrest of cell proliferation, making it particularly effective against rapidly dividing cells. Podophyllotoxin is primarily used in the treatment of external genital warts caused by certain types of human papillomavirus (HPV). Its ability to inhibit cell division makes it an effective treatment for these hyperproliferative skin conditions. Moreover, due to its targeted action, it is employed in topical formulations for direct application to affected areas. Researchers are also exploring its potential in other therapeutic areas, given its mechanism of interfering with cellular replication. Despite its therapeutic benefits, careful handling and appropriate dosing are essential, considering its potent bioactivity.Formula:C22H22O8Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:414.41 g/mol
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