CAS 52200-48-3: 3-Bromo-2-chloropyridine

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

3-Bromo-2-chloropyridine

3-Bromo-2-chloropyridine is a synthetic chemical that acts as a nucleophile. It can be used for the synthesis of 5-hydroxytryptamine (5-HT) and serotonin, which are important neurotransmitters in the brain that regulate mood. 3-Bromo-2-chloropyridine has been shown to cross link with human cells in culture, suggesting it may have clinical development potential for treating depression. The compound has also been shown to inhibit s-adenosylhomocysteine hydrolase, an enzyme involved in the metabolism of catecholamines, by acting as a competitive inhibitor. This inhibition results in an increase in catecholamine levels and may lead to improved depressive symptoms.