6-Methyl-3-pyridineacetonitrile, with the CAS number 52426-67-2, is an organic compound characterized by its pyridine ring structure, which is a six-membered aromatic ring containing one nitrogen atom. This compound features a methyl group at the 6-position and a cyano group (nitrile) attached to the 3-position of the pyridine ring. It is typically a colorless to pale yellow liquid or solid, depending on its physical state at room temperature. The presence of the cyano group imparts notable polarity and reactivity, making it useful in various chemical syntheses and applications, particularly in the pharmaceutical and agrochemical industries. The compound is soluble in polar organic solvents, and its properties may include moderate volatility and potential toxicity, necessitating careful handling. As with many nitriles, it may undergo hydrolysis to form corresponding carboxylic acids under appropriate conditions. Overall, 6-Methyl-3-pyridineacetonitrile is a valuable intermediate in organic synthesis, contributing to the development of more complex chemical entities.

6-Methyl-3-pyridineacetonitrile

52426-67-2: 2-(6-Methylpyridin-3-yl)acetonitrile, 3-Pyridineacetonitrile, 6-Methyl-, 6-Methyl-3-pyridineacetonitrile, (6-Methylpyridin-3-yl)acetonitrile

Applications 6-Methyl-3-pyridineacetonitrile is a reactant used in the preparation of pyrazolopyrimidine derivatives as agents for treatment of autoimmune diseases and orally active corticotropin-releasing factor receptor antagonists.
References Chen, C. et al.: J. Med. Chem., 47, 4787 (2004)


CAS 52426-67-2: 6-Methyl-3-pyridineacetonitrile

6-Methyl-3-pyridineacetonitrile

Ref: TR-M337915

(6-Methylpyridin-3-yl)acetonitrile

Ref: 54-OR46596

2-(6-Methylpyridin-3-yl)acetonitrile

Ref: 10-F321477

6-Methyl-3-pyridineacetonitrile

Ref: IN-DA00DF8R

2-(6-Methylpyridin-3-yl)acetonitrile

Ref: 3D-CCA42667