CAS: 52441-38-0

Saikosaponin B is a bioactive compound, classified as a triterpenoid saponin, which is derived from the roots of the Bupleurum chinense plant. It exerts its effects primarily by modulating immune responses and inhibiting inflammatory pathways, including the downregulation of pro-inflammatory cytokines and the inhibition of the NF-κB signaling pathway. Saikosaponin B has shown potential in various pharmacological applications, particularly in the treatment of liver diseases such as hepatitis and liver fibrosis, due to its hepatoprotective effects. Additionally, its anti-inflammatory properties make it a candidate for managing conditions associated with chronic inflammation, including certain autoimmune diseases. Research into its mechanisms suggests roles in antioxidant activities and modulation of macrophage functions, thus contributing to its therapeutic potential. Scientists are also exploring its use as an adjuvant in enhancing the efficacy of conventional therapies. Overall, Saikosaponin B represents a promising target for further investigation in drug development aimed at addressing complex inflammatory and immune-mediated illnesses.