CAS: 524708-03-0

APE1 Inhibitor III is a molecule that inhibits the protein transport APE1. It has been shown to inhibit cellular physiology and suppress the m2 phenotype in granule neurons. This inhibitor is able to block the progression of prostate cancer cells, hematopoietic cells, and leukemias by preventing the binding of proteins to DNA. APE1 Inhibitor III also has pluripotent activities, which could lead to future treatments for diseases such as Alzheimer's disease.

APE1-IN-1 is a purine/pyrimidine-free endonuclease 1 inhibitor with potential antitumor activity that enhances the toxicity of alkylating agents on cancer cells