CAS: 524962-01-4

Bekm 1 is a peptide that binds to the nicotinic acetylcholine receptor and activates it. This receptor is found on the post-synaptic membrane of neurons, which are responsible for transmitting messages from one nerve cell to another. Bekm 1 is an agonist at this receptor, which means that it binds to the receptor and triggers a response. The activation of these receptors has been shown to inhibit neuronal activity.

Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.