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CAS 52665-69-7: Calcimycin

Formula:C29H37N3O6
InChI:InChI=1S/C29H37N3O6/c1-15-10-11-29(17(3)13-16(2)27(38-29)18(4)26(33)20-7-6-12-31-20)37-22(15)14-23-32-25-21(36-23)9-8-19(30-5)24(25)28(34)35/h6-9,12,15-18,22,27,30-31H,10-11,13-14H2,1-5H3,(H,34,35)/t15-,16-,17-,18-,22-,27+,29+/m1/s1
InChI key:InChIKey=HIYAVKIYRIFSCZ-CYEMHPAKSA-N
SMILES:C[C@H]1[C@]2(O[C@]([C@@H](C(=O)C3=CC=CN3)C)([C@H](C)C1)[H])O[C@H](CC4=NC=5C(O4)=CC=C(NC)C5C(O)=O)[C@H](C)CC2
Synonyms:
  • 1,7-Dioxaspiro[5.5]undecane, 4-benzoxazolecarboxylic acid deriv.
  • 4-Benzoxazolcarbonsaure, 5-(Methylamino)-2-[[3,9,11-trimethyl-8-[1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-, [6S-[6α(2S*,3S*),8β(R*),9β,11α]]-
  • 4-Benzoxazolecarboxylic acid, 5-(methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-
  • 4-Benzoxazolecarboxylic acid, 5-(methylamino)-2-[[(2R,3R,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-
  • 5-(Methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid
  • A 23187
  • Antibiotic A 23187
  • Calcimycin
  • Calcium ionophore A 23187
  • Calcium ionophore III
  • Calimycin
  • See more synonyms
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Found 8 products.
  • Antibiotic A23187, 98%
    Alfa Aesar By Thermo Fisher Scientific
    + Info

    Antibiotic A23187, 98%

    CAS:
    A23187 (Mixed Calcium-Magnesium Salt) is used in cell activation experiments when calcium dose-response data are not required. Ca-Mg ratio ∼ 1:1. it is widely used as a compound in cell activation. It is used as a highly selective Ca2+ ionophore. it is used in studies of intracellular Ca2+ mediated events. A23187 has been observed to induce cell activation, differentiation or proliferation. In vitro experimentation has shown A23187 to boost ROS generation and platelet fragmentation. A23187 is a widely used ionophore. It has the ability to increase the intracellular concentrations of cations and is widely used to increase the intracellular levels of calcium. Visualization of Synaptic Ca2+ Calmodulin-Dependent Protein Kinase II Activity in Living Neurons. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
    Formula:C29H37N3O6
    Purity:98%
    Molecular weight:523.62

    Ref: 02-J63020

    10mg
    To inquire
  • A23187, 98%, free acid
    Acros
    + Info

    A23187, 98%, free acid

    CAS:
    This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
    Formula:C29H37N3O6
    Purity:98%
    Color and Shape:White to off-white, Solid
    Molecular weight:523.63

    Ref: AC-32808

    1mg
    Discontinued
    Discontinued product
  • Calcimycin A23187
    Apollo Scientific
    + Info

    Calcimycin A23187

    CAS:
    Calcimycin A23187
    Formula:C29H37N3O6
    Purity:By hplc: 98.90% (Typical Value in Batch COA)
    Color and Shape: white powder
    Molecular weight:523.62g/mol

    Ref: 54-BIC1006

    5mg
    130.00€
    10mg
    216.00€
    25mg
    448.00€
    50mg
    788.00€
    100mg
    1,285.00€
    250mg
    2,805.00€
  • Calcium Ionophore A23187
    Biosynth
    + Info

    Calcium Ionophore A23187

    CAS:
    Calcium ionophore A23187 is an ionophore that binds to calcium ions, which then disrupts the membrane and inhibits cell function. Calcium ionophore A23187 has been shown to be effective in inducing apoptosis in human polymorphonuclear leukocytes and also as a model system for studying the apoptosis pathway. This drug has inhibitory properties against a wide range of natural compounds and pluripotent cells.
    Formula:C29H37N3O6
    Purity:Min. 98 Area-%
    Color and Shape:Powder
    Molecular weight:523.62 g/mol

    Ref: 3D-FC137477

    1mg
    Discontinued
    2mg
    Discontinued
    5mg
    Discontinued
    10mg
    Discontinued
    25mg
    Discontinued
    Discontinued product
  • A23187
    TRC
    + Info

    A23187

    Controlled Product
    CAS:
    Applications A23187 is calcium channel modulator; Highly selective Ca2+ ionophore. References Khin, P. P., et al.: Pharmacol., 99, 216-225 (2017); Han, N., et al.: Chin. Exp. Pharmacol. Physiol., 44, 257-265 (2017)
    Formula:C29H37N3O6
    Color and Shape:Neat
    Molecular weight:523.62

    Ref: TR-A965310

    10mg
    348.00€
  • Calcimycin
    Targetmol
    + Info

    Calcimycin

    CAS:
    Calcimycin (A-23187) is a polyether antibiotic that transports Ca²⁺, uncouples phosphorylation, and inhibits ATPase in mitochondria.
    Formula:C29H37N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:523.62

    Ref: TM-T10662L

    1mg
    134.00€
  • Calcium Ionophore A23187
    Glentham
    + Info

    Calcium Ionophore A23187

    CAS:
    Formula:C29H37N3O6
    Purity:≥ 98%
    Color and Shape:White powder
    Molecular weight:523.62

    Ref: 7W-GE5436

    1mg
    48.00€
    5mg
    118.00€
    10mg
    195.00€
  • A23187
    Indagoo
    + Info

    A23187

    CAS:
    Formula:C29H37N3O6
    Purity:97%
    Color and Shape:Solid
    Molecular weight:523.6205799999999

    Ref: IN-DA00D7WY

    1mg
    118.00€
    5mg
    254.00€
    25mg
    To inquire