2-Methylbenzamide, with the CAS number 527-85-5, is an organic compound belonging to the class of amides. It features a benzene ring substituted with a methyl group and an amide functional group, which contributes to its chemical properties. This compound is typically a white to off-white solid at room temperature and is known for its moderate solubility in polar solvents like water, while being more soluble in organic solvents such as ethanol and acetone. The presence of the amide group imparts characteristics such as hydrogen bonding capabilities, influencing its reactivity and interactions with other molecules. 2-Methylbenzamide is often utilized in organic synthesis and may serve as an intermediate in the production of pharmaceuticals and agrochemicals. Its melting and boiling points, along with its density, can vary based on purity and environmental conditions. Safety data indicates that, like many amides, it should be handled with care, as it may pose health risks if ingested or inhaled.

2-Methylbenzamide

527-85-5: 2-Methylbenzamide, 2-Toluamide, Benzamide, 2-methyl-, NSC 2169, o-Methylbenzamide, o-Toluic amide, o-Toluamide

2-Methylbenzamide is an amide with a carbonyl group and an intramolecular hydrogen. It has been shown to have synergic effects when combined with piperonyl butoxide in the treatment of autoimmune diseases. This synergistic effect is due to the inhibition of inflammatory mediator release, which can be achieved by blocking the enzyme cyclooxygenase-2. 2-Methylbenzamide has also been shown to inhibit deuterium isotope effect in cd-1 mice, which could make it beneficial for patients who are unable to tolerate other drugs.

CAS 527-85-5: 2-Methylbenzamide

2-Methylbenzamide

Ref: IN-DA003HOJ

2-Methylbenzamide

Ref: 3D-FM71127

o-Toluamide

Ref: 54-OR451329

O-Toluamide

Ref: 10-F341826