CAS 529-05-5: Chamazulene

Chamazulen analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Aromatic hydrocarbon

Chamazulene (Dimethulene) is a terpenoid obtained from Matricaria chamomilla. It possesses anti-inflammatory and antioxidant activity, inhibits leukotriene B4.

Chamazulene is an aromatic chemical compound that functions as a natural anti-inflammatory agent, which is derived from the essential oil of chamomile flowers (Matricaria recutita and Chamaemelum nobile). This compound is primarily formed during the steam distillation of the chamomile plant, where precursors such as matricin undergo chemical transformation. Chamazulene exhibits its mode of action by inhibiting the synthesis of inflammatory mediators, particularly through the downregulation of cyclooxygenase (COX) and lipoxygenase (LOX) pathways, both of which play a critical role in the inflammatory response. Additionally, it exhibits antioxidant properties by scavenging free radicals, contributing to its therapeutic effects. The applications of chamazulene are significant in various fields of science and medicine. It is utilized in the formulation of anti-inflammatory medications, topical treatments for skin conditions such as eczema and dermatitis, and is also explored for its potential in treating respiratory and gastrointestinal disorders. Chamazulene's pharmacological effects are continuously studied to expand its potential uses, owing to its effectiveness and natural origin.