CAS 53-86-1: Indomethacin
Formula:C19H16ClNO4
InChI:InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
InChI key:InChIKey=CGIGDMFJXJATDK-UHFFFAOYSA-N
SMILES:C(=O)(N1C=2C(C(CC(O)=O)=C1C)=CC(OC)=CC2)C3=CC=C(Cl)C=C3
Synonyms:- 1-(4-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid
- 1-(4-Chlorobenzoyl)-5-Methoxy-2-Methylindol-3-Ylacetic Acid
- 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid
- 1-(4-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
- 1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid
- 1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid
- 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acid
- 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
- 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-
- 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
- 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
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Indometacin impurity mixture CRS
CAS:Indometacin impurity mixture CRSFormula:C17H19N3Molecular weight:265.3529INDOMETACIN CRS
CAS:INDOMETACIN CRSFormula:C17H19N3Color and Shape:Crystalline Powder. White. Yellow. Powder.Molecular weight:265.3529Indomethacin
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C19H16ClNO4Color and Shape:White to yellow to light beige, Crystalline powder, May have a pink hueMolecular weight:357.79Indomethacin
CAS:Formula:C19H16ClNO4Purity:≥ 98.0% (dried basis)Color and Shape:White to off-white or pale pink powderMolecular weight:357.80Indomethacin
CAS:Controlled ProductImpurity Acemetacin EP Impurity B Applications Inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)Formula:C19H16ClNO4Color and Shape:BeigeMolecular weight:357.79Indomethacin (Indometacin) EP Impurity D
CAS:Formula:C19H16ClNO4Color and Shape:White To Off-White SolidMolecular weight:357.79Indomethacin - Bio-X ™
CAS:Indomethacin is a nonsteroidal anti-inflammatory drug that inhibits the production of prostaglandin PGE2. It is used to treat pain, fever, and inflammation. Indomethacin's mechanism of action is not well understood, but it may be due to interference with the ability of PMNs to bind to the surface of bacteria or to release reactive oxygen species. The drug has been shown to reduce mitochondrial membrane potential in mammalian cells, leading to apoptosis. This effect on mitochondria may also contribute to Indomethacin's anti-inflammatory effects. Indomethacin is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C19H16ClNO4Purity:(%) Min. 95%Color and Shape:PowderMolecular weight:357.79 g/molIndomethacin
CAS:Analgesics, antipyretics and non-hormonal anti-inflammatory agentsFormula:C19H16ClNO4Color and Shape:PowderMolecular weight:357.79Indomethacin, 99+%
CAS:Non-selective cyclooxygenase inhibitorIndomethacin acts as an antiinflammatory, antipyretic and analgesic. It serves as an inhibitor cyclooxygenase such as Cox-1 and Cox-2. In addition to this, it is used as a prescription medication in order to reduce fever, stiffness, swelling and pain. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C19H16ClNO4Purity:99+%Molecular weight:357.8Indomethacin, 98%
CAS:It is a non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. It finds its application as gout suppressant, non-steroidal anti-inflammatory drug and analgesic. It also plays many biological roles. Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor γ), a ligand-activated transcription factor known to play an important role in adipogenesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C19H16ClNO4Purity:98%Color and Shape:White to pale cream, PowderMolecular weight:357.79Indomethacin
CAS:Indomethacin is a nonsteroidal anti-inflammatory drug that inhibits the production of prostaglandin PGE2. It is used to treat pain, fever, and inflammation. Indomethacin also has significant cytotoxicity in vitro and produces a dose-dependent reduction in polymorphonuclear leucocytes (PMNs). Indomethacin's mechanism of action is not well understood, but it may be due to interference with the ability of PMNs to bind to the surface of bacteria or to release reactive oxygen species. The drug has been shown to reduce mitochondrial membrane potential in mammalian cells, leading to apoptosis. This effect on mitochondria may also contribute to indomethacin's anti-inflammatory effects.Formula:C19H16ClNO4Purity:Min. 95%Color and Shape:White PowderMolecular weight:357.79 g/molIndomethacin
CAS:Indomethacin (Indomethacin) is a inhibitor of COX1 and COX2. Indomethacin is a non-steroidal anti-inflammatory agent. Cost-effective and quality-assured.Formula:C19H16ClNO4Purity:99.27% - 99.76%Color and Shape:Pale-Yellow To Yellow-Tan Crystalline Powder Physical Description Crystals (Ntp 1992)Molecular weight:357.79Indomethacin
CAS:Formula:C19H16ClNO4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:357.79
