Ethyl 4-hydroxy-2-methylpyrimidine-5-carboxylate, with the CAS number 53135-24-3, is a chemical compound that belongs to the class of pyrimidine derivatives. This substance features a pyrimidine ring substituted with a hydroxyl group at the 4-position and a carboxylate group at the 5-position, along with an ethyl ester at the carboxylic acid site. It is typically characterized by its moderate solubility in polar solvents due to the presence of both hydrophilic (hydroxyl and carboxylate) and hydrophobic (ethyl group) functional groups. The compound may exhibit biological activity, potentially serving as a precursor or intermediate in the synthesis of pharmaceuticals or agrochemicals. Its structural features suggest it could participate in hydrogen bonding, influencing its reactivity and interactions in various chemical environments. As with many organic compounds, safety data should be consulted for handling and usage, as it may pose health risks if not managed properly.

ethyl 4-hydroxy-2-methylpyrimidine-5-carboxylate

53135-24-3: 4-Hydroxy-2-Methyl-Pyrimidine-5-Carboxylic Acid Ethyl Ester

4-Hydroxy-2-methyl-pyrimidine-5-carboxylic acid ethyl ester is a potent inhibitor of human telomerase. The enzyme telomerase is involved in the synthesis of telomeres, which are repetitive DNA sequences at the ends of chromosomes that protect the chromosomes from deterioration or from fusion with other chromosomes. Telomeres shorten during each cell division, and eventually become too short to protect the chromosome. This leads to chromosomal instability and cell death. 4-Hydroxy-2-methyl-pyrimidine-5-carboxylic acid ethyl ester inhibits human telomerase by binding to it and preventing telomere replication. This drug has been shown to inhibit tumor growth in mice when used in combination with chemotherapy drugs.

CAS 53135-24-3: ethyl 4-hydroxy-2-methylpyrimidine-5-carboxylate

4-Hydroxy-2-methyl-pyrimidine-5-carboxylic acid ethyl ester

Ref: 3D-FH165241

4-Hydroxy-2-methyl-pyrimidine-5-carboxylic acid ethyl ester

Ref: 10-F024808

4-HYDROXY-2-METHYL-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER

Ref: IN-DA00DAN3