CAS 532-32-1: Benzoic acid, sodium salt

Sodium benzoate is a food additive that is used as an antimicrobial agent and preservative. It has been shown to have synergistic effects when combined with sodium citrate for the treatment of cancerous skin lesions in mice. This synergistic effect has also been observed using electrochemical impedance spectroscopy on mitochondria from rat brain cells. Sodium benzoate has also been found to inhibit the production of neurotrophic factors such as nerve growth factor and brain-derived neurotrophic factor, which are required for neuronal development. Sodium benzoate can be used to identify DNA mutations by fluorescence probe labeling and synchronous fluorescence imaging.

Sodium Benzoate

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications Sodium Benzoate is used in the synthesis of 5-pyrazolinone derivatives as analgesic agents. Also used in the preparation of aminoflavones and trihydroxylbenzoyl flavonoid analogs as α-glucosidase inhibitors. References Gursoy, A. et al.: Eur. J. Med. Chem., 35, 359 (2000); Gao, H, Bioorg. Med. Chem., 13, 1661 (2005);