CAS 5326-23-8: 6-Chloronicotinic acid

Applications 6-Chloronicotinic Acid, is an organic building block used for the synthesis of various biologically active compounds, including inhibitors. It is an intermediate for the synthesis of N-(thiophen-2-yl) benzamide derivatives as BRAFV600E inhibitors, and novel DNA-gyrase B inhibitors. References Xie, Y., et al.: Bioorg. Med. Chem. Lett., 23, 2306 (2013); Shiroya, U., et al.: Med. Chem. Res., 22, 5227 (2013);

6-Chloropyridine-3-carboxylic acid (6-chloronicotinic acid/6-CNA) has been used to study its photolytic and photocatalytic degradation. The product has been used as a media component during the isolation of 6-CNA degrading bacterial strain from imidacloprid-exposed soil samples. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

6-Chloronicotinic acid is a chemical compound that can be used as an analytical method. It is a fluorescent probe that is used to identify the presence of imidacloprid in a sample. This compound reacts with imidacloprid and changes its fluorescence properties. The 6-chloronicotinic acid fluoresces green when it binds to imidacloprid, which has been shown to have toxicological properties. 6-Chloronicotinic acid is also used in determining the concentration of neonicotinoids in samples by using a reaction mechanism involving hydrogen peroxide and hypochlorous acid. The reaction produces chlorinated products that are measured using a fluorescence detector. This process can be done without any interfering matrix effect, making it more accurate than traditional methods. 6-Chloronicotinic acid can also be used for the blood sampling of animals, such as mice, due to its synchronous fluorescence property. It binds with hem

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

6-Chloronicotinic acid