CAS 5348-42-5: 4,5-Dichloro-1,2-phenylenediamine

4,5-Dichlorobenzene-1,2-diamine

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications 4,5-Dichloro-phenylenediamine (cas# 5348-42-5) is a compound useful in organic synthesis.

4,5-Dichloro-1,2-phenylenediamine is a cytotoxic agent that can inhibit the enzymes urea amidolyase and fatty acid synthase in tissue culture. This compound also inhibits the production of urea nitrogen and fatty acids in human serum. 4,5-Dichloro-1,2-phenylenediamine may be useful as a cancer treatment because it has been shown to cause leukemia cell death as well as inhibition of t-cell proliferation. The drug may also induce apoptosis by inhibiting DNA synthesis through its reaction with benzimidazole compounds. The basic structure of 4,5-Dichloro-1,2-phenylenediamine is similar to protocatechuic acid and malignant brain tumor cells.