The chemical substance known as 2-[3-[4-(3-chloro-4-hydroxy-phenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one, with the CAS number 53818-10-3, is a complex organic compound characterized by its multi-cyclic structure, which includes a triazole and a pyridine moiety. This compound features a piperazine ring, which is often associated with pharmacological activity, particularly in the realm of neuropharmacology. The presence of a chloro and hydroxy group on the phenyl ring suggests potential for hydrogen bonding and increased solubility in polar solvents. The triazole and pyridine components contribute to the compound's potential biological activity, possibly influencing its interaction with various biological targets. Such compounds are often investigated for their therapeutic applications, including but not limited to, anti-anxiety, antidepressant, or antipsychotic effects. The specific arrangement of functional groups and the overall molecular architecture play a crucial role in determining the compound's reactivity, stability, and biological efficacy.

2-[3-[4-(3-chloro-4-hydroxy-phenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one

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4'-Hydroxy trazodone

Applications The main metabolite of Trazodone-HCl (T718500).
References Yamato, C., et al.: Xenobiotica, 4, 765 (1974), Hull, M., et al.: Br. Med. J., 309, 378 (1994), Garcia-Pando, A., et al.: J. Clin. Psychiatry, 63, 135 (2002), Kalgutkar, A., et al.: Curr. Drug Metab., 3, 379 (2002), Kalgutkar, A., et al.: Drug Metab. Dispos., 33, 243 (2005),


4’-Hydroxy Trazodone

Trazodone Impurity 7

4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone.1It is an inhibitor of organic anion transporter 3 (OAT3; Ki= 16.9 μM) and is

CAS 53818-10-3: 2-[3-[4-(3-chloro-4-hydroxy-phenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one

4'-Hydroxy trazodone

Ref: 3D-FH24148

4’-Hydroxy Trazodone

Ref: TR-H970020

Trazodone Impurity 7

Ref: 4Z-T-3326

4'-hydroxy Trazodone

Ref: TM-T35721