CAS 53823-03-3: 4-hydroxy-6-(2-hydroxyethyl)-2-(hydroxymethyl)-2,5,7-trimethyl-2,3-dihydro-1H-inden-1-one

Onitisin is an antimicrobial agent, which is derived from microbial sources with the primary mode of action being the inhibition of bacterial cell wall synthesis. This compound is designed to disrupt the peptidoglycan layers essential for bacterial growth and survival, specifically targeting gram-positive bacteria. The bactericidal properties of Onitisin stem from its ability to bind to transpeptidase enzymes, crucial for cross-linking peptidoglycan chains, effectively halting bacterial proliferation. The applications of Onitisin span various scientific and medical fields, particularly in the development of antibiotic therapies targeting resistant bacterial strains. Researchers use this compound to study mechanisms of bacterial resistance and to develop new antibiotics with enhanced efficacy. In clinical microbiology, it serves as a valuable tool for understanding bacterial physiology and the dynamics of infection. Additionally, Onitisin is instrumental in laboratories investigating the synthesis of novel antibiotic derivatives, aiming to combat the growing threat of antimicrobial resistance. The compound’s precise action and effectiveness make it a vital resource in the ongoing battle against infectious diseases.

Onitisin, onitinoside and onitin can inhibit the contraction of isolated guinea-pig ileum.