CAS 53823-08-8: Cascaroside A
Formula:C27H32O14
InChI:InChI=1S/C27H32O14/c28-6-9-4-11-16(26-24(37)22(35)19(32)14(7-29)39-26)10-2-1-3-13(18(10)21(34)17(11)12(31)5-9)40-27-25(38)23(36)20(33)15(8-30)41-27/h1-5,14-16,19-20,22-33,35-38H,6-8H2/t14-,15-,16+,19-,20-,22+,23+,24-,25-,26+,27-/m1/s1
InChI key:InChIKey=MNAYRSRTNMVAPR-ZHVWOXMGSA-N
SMILES:O[C@H]1[C@]([C@]2(C=3C(=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=CC3)C(=O)C=5C2=CC(CO)=CC5O)[H])(O[C@H](CO)[C@@H](O)[C@@H]1O)[H]
Synonyms:- 9(10H)-Anthracenone, 10-β-D-glucopyranosyl-8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-, (10S)-
- Cascaroside A
- (10S)-10-β-D-Glucopyranosyl-8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
- 9(10H)-Anthracenone, 10-β-D-glucopyranosyl-8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-, (S)-
- See more synonyms
Sort by
Found 4 products.
Cascaroside A
CAS:Cascaroside A is a natural anthraquinone glycoside, which is extracted primarily from the bark of Rhamnus purshiana, commonly known as cascara sagrada. This glycoside functions by stimulating peristalsis in the colon, primarily through an interaction with nerve cells in the colon wall. The enzymatic hydrolysis of Cascaroside A in the digestive tract releases anthraquinones, which act as irritants to the intestinal mucosa. This irritation prompts increased peristaltic action and moisture retention in the bowel. The primary use of Cascaroside A is as a laxative, valuable in treating short-term constipation or preparing the bowel for diagnostic procedures such as colonoscopy. It is essential in pharmacological research for understanding the mechanisms of anthraquinone derivatives and their impact on intestinal motility. Moreover, due to its natural origin, it serves as a reference compound in evaluating the potency and efficacy of synthetic laxatives, aiding in the development of safer, more effective gastrointestinal therapies. Its application extends to ethnopharmacology, highlighting the historical use of botanical extracts in traditional medicine.Formula:C27H32O14Purity:Min. 95%Molecular weight:580.5 g/molCascaroside a
CAS:Natural glycosideFormula:C27H32O14Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:580.53
