CAS 53861-34-0: Cascaroside B
Formula:C27H32O14
InChI:InChI=1S/C27H32O14/c28-6-9-4-11-16(26-24(37)22(35)19(32)14(7-29)39-26)10-2-1-3-13(18(10)21(34)17(11)12(31)5-9)40-27-25(38)23(36)20(33)15(8-30)41-27/h1-5,14-16,19-20,22-33,35-38H,6-8H2/t14-,15-,16-,19-,20-,22+,23+,24-,25-,26+,27-/m1/s1
InChI key:InChIKey=MNAYRSRTNMVAPR-OPEXUXIQSA-N
SMILES:O[C@H]1[C@]([C@@]2(C=3C(=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=CC3)C(=O)C=5C2=CC(CO)=CC5O)[H])(O[C@H](CO)[C@@H](O)[C@@H]1O)[H]
Synonyms:- 9(10H)-Anthracenone, 10-β-D-glucopyranosyl-8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-, (10R)-
- 9(10H)-Anthracenone, 10-β-D-glucopyranosyl-8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-, (R)-
- Cascaroside B
- (10R)-10-β-D-Glucopyranosyl-8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
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Cascaroside B
CAS:Cascaroside B is a naturally occurring glycoside compound, which is derived from the cascara plant (Rhamnus purshiana), a species known for its medicinal properties. The compound functions primarily as an anthraquinone glycoside, exerting its mode of action through the stimulation of peristalsis in the colon. This activity is facilitated by the irritation of the intestinal mucosa, resulting from the biotransformation of the cascaroside into its active form by gut flora. The primary application of Cascaroside B is its use as a laxative. It is utilized in both clinical and over-the-counter settings to alleviate constipation by facilitating bowel movements. In a research context, Cascaroside B may also be of interest for studies focusing on gastrointestinal motility and the pharmacokinetics of glycoside-derived medications. Although effective, its use is generally advised to be short-term due to potential risks of dependency and altered bowel function with prolonged use. Cascaroside B thus remains a significant compound in the pharmacological study and treatment of bowel motility disorders.Formula:C27H32O14Purity:Min. 95%Molecular weight:580.53 g/mol
