CAS 53882-12-5: Lodoxamide

Applications Lodoxamide-15N2,d2 is the labelled form of Lodoxamide which is an antiallergic drug that acts as a mast cell stabilizer. It is effective in the treatment of allergic conjunctivitis and in decreasing vascular permeability. References Ciprandi, G., et al.: Allergy, 51(12), 946-951 (1996); Bayer, Atilla., et al.: Ophthalmologica, 217(2), 119-123 (2003)

Lodoxamide

Lodoxamide (Lodoxamidum) is an antiallergic drug acting as a mast-cell stabilizer. It is effective in the treatment of asthma and allergic conjunctivitis.

Stability Hygroscopic Applications Lodoxamide is an antiallergic drug that acts as a mast cell stabilizer. It is effective in the treatment of allergic conjunctivitis and in decreasing vascular permeability. References Ciprandi, G., et al.: Allergy, 51(12), 946-951 (1996); Bayer, Atilla., et al.: Ophthalmologica, 217(2), 119-123 (2003)

Lodoxamide is a type of ophthalmic medication known as a mast cell stabilizer, which is chemically synthesized from non-steroidal structures. It works by inhibiting the degranulation of sensitized mast cells and subsequent release of inflammatory mediators such as histamine. This action is achieved through the stabilization of the cell membrane of mast cells, thus preventing cellular activation. Lodoxamide is primarily used in the treatment and management of allergic ocular conditions, such as vernal keratoconjunctivitis and allergic conjunctivitis. By reducing the release of histamine and other inflammatory mediators, lodoxamide decreases the symptoms associated with these allergic reactions, which include itching, redness, and swelling of the eyes. By targeting specific pathways of the immune response, lodoxamide offers a therapeutic approach that differs from antihistamines, presenting a valuable tool in managing chronic and acute ocular allergies.