CAS 5390-04-5: 4-Pentyn-1-ol

4-Pentyn-1-ol is a molecule with the chemical formula of C10H18O. It has intramolecular hydrogen, hydroxyl group and methyl ketones. 4-Pentyn-1-ol is used as a solvent and in perfumery. This compound can be synthesized by hydrochloric acid, hydrogen bond and proton. The FTIR spectroscopy of 4-pentyn-1-ol shows that it has a broad absorption band at 3300 cm−1 and a sharp peak at 1750 cm−1 which are assigned to the O-H stretching vibrations in the hydroxyl group. The IR spectrum also indicates that this compound has an intramolecular hydrogen bond. 4 pentyn - 1 - ol

4-Pentyn-1-ol

Applications 4-Pentyn-1-ol is an alkyne alcohol that is used as an initiator in ring-opening polymerization reactions. 4-Pentyn-1-ol is capable of undergoing cyclosisomerization, and is also used as a reactant in the synthesis of (+)-Serinolamide A, a cannabinoid CB1 receptor agonist. References Gao, Y., et al.: Tetrahedron Lett., 54, 6511 (2013); Liao, R., et al.: Proc. Nat. Acad. Sci., 107, 22523 (2010); Miranda, P., et al.: Org. Lett., 5, 1979 (2003); Xu, N., et al.: Macromol. Chem. Phys., 208, 730 (2007)

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

4-Pentyn-1-ol is widely utilized in ring-opening polymerization reactions. It plays an important role as a starting reagent in stereo selective total synthesis of antimicrobial marine metabolites, ieodomycin A and B. It is also used in the preparation of 3-pent-4-ynyloxy phthalonitrile. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.