CAS 541-16-2: 1,3-Bis(1,1-dimethylethyl) propanedioate

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Di-tert-butyl malonate, is used as a pharmaceutical intermediate. it can be used to produce Diazomalonsaeure-di-tert-butylester at the ambient temperature. It will need reagents cesium carbonate, p-toluenesulfonyl azide and solvent tetrahydrofuran with the reaction time of 1 hour. T This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Di-tert-butyl malonate

Di-tert-butyl malonate is a synthetic, organic compound that belongs to the group of quinoline derivatives. It is used as a reagent in the synthesis of other organic compounds. The compound has been shown to be effective against metabolic disorders, such as fatty acid oxidation disorders and ketoacidosis. In addition, it has been shown to reduce levels of trifluoroacetic acid, which can accumulate in the body due to an imbalance in metabolic processes. Di-tert-butyl malonate can be synthesized from aryl halides and trifluoroacetic acid in the presence of an acidic catalyst such as hydrochloric acid or hydroxide solution.