CAS 541-59-3: Maleimide

Reacts quantitatively with sulfhydryl groups.Maleimide is used to immobilize the bovine serum albumin-boronic acid conjugates in association with silica beads. Its nanoparticle surface favors the conjugation with cell penetration peptides. It is involved in Rhodium-catalyzed conjugate arylation with arylboronic acids. It is actively involved in Michael additions and Diels-Alder reactions by the addition across the double bond. It acts as crosslinking reagents in polymer chemistry. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Maleimide is a chemical compound that can be synthesized from maleic anhydride and hydrogen fluoride. It has been used as a fluorescent probe for the measurement of electrochemical impedance spectroscopy (EIS) in biological systems. Maleimide is also used to study the interaction with mouse monoclonal antibody, which can be used to detect the presence of specific proteins or antigens in blood. Maleimides are covalently linked to proteins and other macromolecules through their thiol groups, forming a stable linkage. Maleimide reacts with hydrogen gas at high temperatures, leading to a decrease in its redox potentials. The reaction solution can be analyzed by plasma mass spectrometry, which determines the concentration of maleimide and its reactants by measuring ions produced by ionization or fragmentation reactions.

Maleimide

Maleimide surface group on nanoparticles allows simple conjugation with peptides via click chemistry, preserving biofunctions.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Maleimide

Applications Maleimide (cas# 541-59-3) is a compound useful in organic synthesis. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package