4-Bromo-2-hydroxybenzamide, with the CAS number 5428-40-0, is an organic compound characterized by the presence of a bromine atom and a hydroxyl group on a benzene ring, along with an amide functional group. This compound typically appears as a solid and is soluble in polar solvents due to the hydroxyl group, which can engage in hydrogen bonding. The bromine substituent enhances the compound's reactivity and can influence its biological activity. The presence of the hydroxyl group contributes to its potential as a phenolic compound, which may exhibit antioxidant properties. 4-Bromo-2-hydroxybenzamide can be utilized in various chemical syntheses and may serve as an intermediate in the production of pharmaceuticals or agrochemicals. Its structural features suggest potential applications in medicinal chemistry, particularly in the development of compounds with specific biological activities. As with many organic compounds, safety precautions should be taken when handling it, as it may pose health risks if ingested or inhaled.

4-Bromo-2-hydroxybenzamide

5428-40-0: Benzamide, 4-Bromo-2-Hydroxy-, NSC 12928, 4-Bromo-2-hydroxybenzamide

4-Bromo-2-hydroxybenzamide is a nonlinear, bioisostere molecule with low nanomolar in vivo antitumor activity. It inhibits tumor growth and induces apoptosis by inhibiting the cell cycle at G1 phase. 4-Bromo-2-hydroxybenzamide has been shown to inhibit the growth of cancer cells in vitro and in vivo through its ability to induce apoptosis. This drug has also been shown to selectively target tumor cells, including human breast cancer, colon cancer, and leukemia cells. 4-Bromo-2-hydroxybenzamide has not been shown to cause toxicity in animal models, suggesting that it may be a promising agent for the treatment of cancers that are resistant to current therapies.

CAS 5428-40-0: 4-Bromo-2-hydroxybenzamide

4-Bromo-2-hydroxybenzamide

Ref: 3D-FAA42840

4-Bromo-2-hydroxybenzamide

Ref: 54-OR91196

4-Bromo-2-hydroxybenzamide

Ref: 10-F607562

4-BROMO-2-HYDROXYBENZAMIDE

Ref: IN-DA00DGVB