5-Chloro-2(1H)-pyrimidinone is a heterocyclic organic compound characterized by a pyrimidine ring, which is a six-membered aromatic ring containing two nitrogen atoms at positions 1 and 3. The presence of a chlorine atom at the 5-position and a carbonyl group (C=O) at the 2-position contributes to its reactivity and potential applications in medicinal chemistry. This compound is typically a white to off-white solid and is soluble in polar organic solvents. It exhibits properties that make it useful as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The chlorine substituent can influence the compound's biological activity and lipophilicity, making it a subject of interest in drug design. Additionally, the presence of the pyrimidinone structure allows for hydrogen bonding interactions, which can be crucial in biological systems. Overall, 5-Chloro-2(1H)-pyrimidinone is a valuable compound in organic synthesis and medicinal chemistry due to its unique structural features and reactivity.

5-Chloro-2(1H)-pyrimidinone

54326-16-8: 2(1H)-Pyrimidinone, 5-chloro-, 2-Oxo-5-chloropyrimidine, 2-Pyrimidinol, 5-chloro-, 5-Chloro-1H-pyrimidin-2-one, 5-Chloro-2(1H)-pyrimidinone, 5-Chloro-2-hydroxypyrimidine, 5-Chloro-2-pyrimidone, 5-Chloropyrimidin-2-one, 5-chloropyrimidin-2(1H)-one, Ny 3000

5-Chloro-2-hydroxypyrimidine is a crystalline compound that has been shown to be an inactivator of colchicine. It binds to the active site of the enzyme and prevents the formation of the toxic product, 5-chloro-2,4,6-trimethoxypyrimidine. This compound has also been shown to have dehydrogenase activity in liver cells. At high concentrations, 5-chloro-2-hydroxypyrimidine can inhibit cellular processes such as metaphase and cytokinesis.

CAS 54326-16-8: 5-Chloro-2(1H)-pyrimidinone

5-Chloro-2-hydroxypyrimidine

Ref: 3D-FC12032

5-CHLORO-2-HYDROXYPYRIMIDINE

Ref: IN-DA00DECS

5-Chloro-2-hydroxypyrimidine

Ref: 10-F080041

5-Chloro-2-hydroxypyrimidine

Ref: 54-OR912364