CAS 54364-02-2: 8-(4-Chlorophenylthio)-cGMP
Formula:C16H15ClN5O7PS
InChI:InChI=1S/C16H15ClN5O7PS/c17-6-1-3-7(4-2-6)31-16-19-9-12(20-15(18)21-13(9)24)22(16)14-10(23)11-8(28-14)5-27-30(25,26)29-11/h1-4,8,10-11,14,23H,5H2,(H,25,26)(H3,18,20,21,24)/t8-,10-,11-,14-/m1/s1
InChI key:InChIKey=ZDJHIEHUVPCEDK-IDTAVKCVSA-N
SMILES:S(C=1N(C2=C(N1)C(=O)N=C(N)N2)[C@H]3[C@H](O)[C@]4([C@](O3)(COP(=O)(O)O4)[H])[H])C5=CC=C(Cl)C=C5
Synonyms:- 2-amino-8-[(4-chlorophenyl)sulfanyl]-9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-1,9-dihydro-6H-purin-6-one
- 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, guanosine deriv.
- 6H-purin-6-one, 2-amino-8-[(4-chlorophenyl)thio]-1,9-dihydro-9-[(4aR,6R,7R,7aS)-tetrahydro-2,7-dihydroxy-2-oxido-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-6-yl]-
- 8-(4-Chlorophenylthio)-cGMP
- 8-(p-Chlorophenylthio)-cGMP
- Guanosine, 8-[(4-chlorophenyl)thio]-, cyclic 3′,5′-(hydrogen phosphate)
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Found 2 products.
8-(p-Chlorophenylthio)-cGMP
CAS:8-(p-Chlorophenylthio)-cGMP is a modified nucleoside that has anticancer activity. It inhibits DNA synthesis and the activation of protein kinases, which are enzymes that transmit signals from the cell surface to the nucleus. 8-(p-Chlorophenylthio)-cGMP can also inhibit viral replication by inhibiting the production of new virus particles and by inhibiting the action of reverse transcriptase, an enzyme that converts RNA into DNA.Formula:C16H15ClN5O7PSPurity:Min. 95%Molecular weight:487.81 g/mol
