CAS 5445-51-2: 1,1-Cyclobutanedicarboxylic acid

1,1-Cyclobutanedicarboxylic acid

1,1-Cyclobutanedicarboxylic acid is a chemical compound that belongs to the group of carboxylates. It is a white crystalline solid with an acidic taste. 1,1-Cyclobutanedicarboxylic acid can be synthesized from malonic acid and cyclobutanone in the presence of a strong base. It also has been shown to have anti-cancer properties in cervical cancer cells in vitro. This substance inhibits the growth of cancer cells by binding to copper ions and forming an acid complex that inhibits DNA synthesis. 1,1-Cyclobutanedicarboxylic acid has also been shown to inhibit human serum albumin (HSA) and copper binding which may lead to decreased copper availability for enzymes involved in oxidative stress pathways.

Cyclobutane-1,1-dicarboxylic acid is a high quality reagent that is used as an intermediate in the production of fine chemicals, speciality chemicals, and research chemicals. It is useful as a scaffold for the synthesis of complex compounds and has been used as a building block to synthesize various chemical compounds. Cyclobutane-1,1-dicarboxylic acid can be used as a versatile building block to form various reaction components. This compound has been shown to have usefulness in the synthesis of natural products and pharmaceuticals.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications 1,1-Cyclobutanedicarboxylic Acid is used in the design, studies and structural model of antitumor dicycloplatin a clinical cancer drug. Hydrolysis mechanism of second-generation anticancer drug carboplatin. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Yang, X. Q., et al.: Science China: Chemistry, 53, 1346 (2010); Pavelka, M., et al.: Chem. Eur. J., 13, 10108 (2007)

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.