CAS 5446-02-6: Methyl 4-methoxysalicylate

Methyl 4-methoxysalicylate is a fatty acid derivative that is structurally related to salicylic acid. It has been shown to have minimal inhibitory concentrations against Staphylococcus epidermidis, a bacterium that commonly colonizes the skin. Methyl 4-methoxy salicylate was also able to inhibit the growth of Salmonella typhimurium and Escherichia coli in vitro. It may act by inhibiting bacterial protein synthesis, although this is not yet confirmed. Methyl 4-methoxy salicylate also has antibacterial properties and has been shown to inhibit the growth of S. epidermidis, a bacterium that commonly colonizes the skin. It may act by inhibiting bacterial protein synthesis, although this is not yet confirmed. Methyl 4-methoxy salicylate also has antibacterial properties and has been shown to inhibit the growth of S. epidermid

Methyl 2-hydroxy-4-methoxybenzoate

Applications Methyl 4-Methoxysalicylate, is an organic building block, used for the synthesis of (+)-coriandrone A and B, two bioactive natural products. It can also be used for the preparation of Dimethoxybenzofuran derivatives as potent and selective inhibitors of CYP2A6. References Wang, W., et al.: Org. Biomol. Chem., 11, 6686 (2013); Yamaguchi, Y., et al.: Heterocycles, 87, 1727 (2013);

Methyl 2-hydroxy-4-methoxybenzoate is used in the enantioselective synthesis of (+)-coriandrone A and B, two bioactive natural products. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.