CAS 5466-06-8: Ethyl 3-mercaptopropionate

Ethyl 3-mercaptopropionate is a chemical compound that is used for the synthesis of polymers. It is obtained by the reaction between ethyl chloride and thiourea. Ethyl 3-mercaptopropionate can be recycled, so it does not need to be synthesized from scratch. It has a high affinity for chloride ions, which makes it useful in the production of polymer films. The presence of functional groups on its structure allows it to undergo nucleophilic substitutions with other substances. The film-forming ability of this compound makes it suitable as a matrix material in solid-phase synthesis reactions. This compound can be used to produce various types of polymers, including polyurethane, polyesters and acrylics. When used as a polymerization initiator, ethyl 3-mercaptopropionate can increase the yield of synthetic products by up to 50%.

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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications Ethyl 3-Mercaptopropanoate is a useful synthetic intermediate. It can be used to prepare acylaminobutyldecahydroisoquinolines with HIV protease-inhibiting activities. It can also be used to prepare new anti-MRSA cephalosporins (cephalosporins C zinc salt, C258750). References Ghosh, A., et al.: J. Med. Chem., 37, 1177 (1994); Cho, A., et al.: Bioorg. Med. Chem. Lett., 11, 137 (2001)

Ethyl 3-Mercaptopropionate