1H-Indole-2,3-dicarboxylic acid, with the CAS number 54781-93-0, is an organic compound that features an indole ring structure substituted with two carboxylic acid groups at the 2 and 3 positions. This compound is characterized by its aromaticity due to the indole moiety, which contributes to its stability and reactivity. The presence of the carboxylic acid groups makes it a dicarboxylic acid, allowing for potential interactions such as hydrogen bonding and the formation of salts or esters. It is typically a white to off-white crystalline solid and is soluble in polar solvents like water and alcohols. This compound is of interest in various fields, including medicinal chemistry, due to its potential biological activities, including anti-inflammatory and anticancer properties. Additionally, its derivatives may be explored for applications in organic synthesis and material science. As with many organic acids, it may exhibit acidic behavior in solution, influencing its reactivity and interactions with other chemical species.

1H-indole-2,3-dicarboxylic acid

54781-93-0: Dimethyl indole-2,3-dicarboxylate, dimethyl 1H-indole-2,3-dicarboxylate

Dimethyl Indole-2,3-Dicarboxylate is a potent inhibitor of bacterial growth. It binds to the active site of bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. Dimethyl Indole-2,3-Dicarboxylate inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Dimethyl Indole-2,3-Dicarboxylate also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e

CAS 54781-93-0: 1H-indole-2,3-dicarboxylic acid

Dimethyl Indole-2,3-Dicarboxylate

Ref: 3D-FD56778

Dimethyl 1H-indole-2,3-dicarboxylate

Ref: 10-F220288

Dimethyl 1H-indole-2,3-dicarboxylate

Ref: IN-DA003PKT

Dimethyl 1H-indole-2,3-dicarboxylate

Ref: 54-OR0413