CAS 548-04-9: Hypericin

Hypericin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Component of medicinal plant Hypericum perforatum (St John's wort). It has multifunctional pharmacological properties such as anti-depressive, anti-neoplastic, anti-tumoral activity. The compound is active against viral infections of herpes simplex virus (HSV-1 and HSV-2), murine cytomegalovirus (CMV) and human immunodeficiency virus (HIV-1). Hypericin is inhibitor of monoaminoxidase enzyme (MAO), protein kinase C (PKC), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and cytochrome P450 (CYP).

Quinone

Hypericin

Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.

Red dye (Naphthodianthron derivative) that is natural occurring partly as sodium- and potassium salt. Hypericin has been shown to have antiviral and antiretroviral activity and to inhibit succinoxidase, NADPH-oxidase, tyrosinkinase and protein kinase

Applications Hypericin is an extract from Hypericum perforatum L. hypericaceae (also known as St. John’s wort) and is believed to be an antibiotic/antiviral, specifically acting as a kinase inhibitor. References Valeri, A. et al.: J. Pharm. Pharmacol., 64, 1770 (2012); Tahtouh, T. et al.: J. Med. Chem., 55, 9312 (2012); Arsic, I. et al.: Molecules, 15, 6688 (2010);

Inhibitor of protein kinase C; induces photosynthesized apoptosisHypercin acts as an antibiotic and antiviral. It is involved in the inhibition of enzyme dopamine beta-hydroxylase action. It also exhibits an anti-HIV and anticancer drug. Further, it is useful in photodynamic therapy. In addition to this, it serves as an inhibitor of protein kinase C which induces photosynthesized apoptosis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Hypericin from Hypericum perforatum

Component of medicinal plant Hypericum perforatum (St John's wort). It has multifunctional pharmacological properties such as anti-depressive, anti-neoplastic, anti-tumoral activity. The compound is active against viral infections of herpes simplex virus (HSV-1 and HSV-2), murine cytomegalovirus (CMV) and human immunodeficiency virus (HIV-1). Hypericin is inhibitor of monoaminoxidase enzyme (MAO), protein kinase C (PKC), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and cytochrome P450 (CYP).

Applications Hypericin-d10 is the isotope labelled analog of Hypericin (H998190); an extract from Hypericum perforatum L. hypericaceae (also known as St. John’s wort) that is believed to be an antibiotic/antiviral specifically acting as a kinase inhibitor. References Valeri, A. et al.: J. Pharm. Pharmacol., 64, 1770 (2012); Tahtouh, T. et al.: J. Med. Chem., 55, 9312 (2012); Arsic, I. et al.: Molecules, 15, 6688 (2010)