CAS 5490-27-7: Dihydrostreptomycin sulfate
Formula:C21H41N7O12H2O4S
InChI:InChI=1S/C21H41N7O12.H2O4S/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;1-5(2,3)4/h5-18,26,29-36H,3-4H2,1-2H3,(H4,22,23,27)(H4,24,25,28);(H2,1,2,3,4)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;/m0./s1
InChI key:InChIKey=GSPKOIJAMLDYCY-RMIBZTJPSA-N
SMILES:S(=O)(=O)(O)O.O([C@H]1[C@H](O[C@@H]2[C@@H](NC(=N)N)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]2O)O[C@@H](C)[C@@]1(CO)O)[C@H]3[C@@H](NC)[C@H](O)[C@@H](O)[C@H](CO)O3
Synonyms:- 2,2'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-(hydroxymethyl)-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (1:1)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N,N′-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N<sup>1</sup>,N<sup>3</sup>-bis(aminoiminomethyl)-, sulfate (2:3)
- Didromycin
- Didromycine
- Dihydroestreptomycin Sulphate
- Dihydrostereptomycin Sulfate
- Dihydrostreptomycin 3/2 sulfate
- Dihydrostreptomycin Suflate
- Dihydrostreptomycin Sulfate(2:3)
- Dihydrostreptomycin sesqui-Sulfate
- See more synonyms
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Found 11 products.
DIHYDROSTREPTOMYCIN SULFATE CRS
CAS:DIHYDROSTREPTOMYCIN SULFATE CRSFormula:C21H43N7O16SMolecular weight:681.6684Dihydrostreptomycin sesquisulfate 100 µg/mL in Acetonitrile/Water
CAS:Formula:C21H41N7O12H2O4SColor and Shape:Single SolutionMolecular weight:1461.42Dihydrostreptomycin sesquisulfate, EP
CAS:Dihydrostreptomycin sesquisulfate, EP is an aminoglycoside antibiotic, structurally derived from Streptomyces griseus. This compound originates from microbial biosynthesis, a method which harnesses the natural antibiotic-producing capabilities of microbial cultures. The mode of action of dihydrostreptomycin sesquisulfate involves binding to the 30S subunit of bacterial ribosomes, which interrupts the process of protein synthesis, ultimately leading to bacterial cell death. This antibiotic is primarily used for the treatment and prevention of bacterial infections in veterinary medicine, especially against Gram-negative bacteria. Its effective targeting of protein synthesis makes it particularly useful in settings where other antibiotics may fail due to resistance. Research into dihydrostreptomycin sesquisulfate also includes its use in studying aminoglycoside-resistant bacterial strains, contributing to the understanding and combating of antibiotic resistance.Formula:C21H41N7O12•(H2SO4)1Purity:(Hplc) 94.0 To 102.0%Color and Shape:PowderMolecular weight:1,461.42 g/molDihydrostreptomycin sesquisulfate
CAS:Formula:C21H41N7O121·5H2SO4Purity:≥ 730IU/mg (anhydrous)Color and Shape:White to off-white powderMolecular weight:730.71Dihydrostreptomycin Sesquisulfate
CAS:Stability Hygroscopic Applications A derivative of Streptomycin (S687500) with antimicrobial activity. It is used in veterinary medicine to treat bovine infection and also as an effective antibiotic to control pests found in crops. References Gradin, J.L. et al.: J. Am. Vet. Med. Assoc., 183, 434 (1983); Bishop, J.R. et al.: J. Dairy Sci., 67, 437 (1984); Singh, D.R. et al.: Obi. Chik. Daig. Gak. Ken. Hok., 11, 475 (1979);Formula:C21H41N7O12·3H2O4SColor and Shape:Off-WhiteMolecular weight:1461.42Dihydrostreptomycin sulfate
CAS:Dihydrostreptomycin sulfate (Dihydrostreptomycin sesquisulfate) inhibits protein synthesis by binding to the 30S ribosomal subunit.Formula:C21H41N7O12·5H2SO4Purity:97.38% - 99.05%Color and Shape:SolidMolecular weight:730.71Dihydrostreptomycin sesquisulfate
CAS:Controlled ProductFormula:C21H41N7O12H2O4SColor and Shape:NeatMolecular weight:1461.42Dihydrostreptomycin sesquisulfate
CAS:Dihydrostreptomycin sesquisulfate is an aminoglycoside antibiotic, which is derived from the bacterium Streptomyces griseus. Its mode of action involves binding to the 30S subunit of the bacterial ribosome, leading to the disruption of protein synthesis. This binding interferes with the initiation complex formation, causing misreading of mRNA and ultimately inhibiting bacterial growth. The primary use of dihydrostreptomycin sesquisulfate is in the treatment of infections caused by Gram-negative bacteria. It has been employed in veterinary medicine to address respiratory and gastrointestinal infections in livestock. However, due to its ototoxic and nephrotoxic potential, its use in humans has been largely discontinued in favor of less toxic alternatives. This antibiotic is particularly effective against Mycobacterium tuberculosis and other mycobacteria, offering a robust option in combating bacterial diseases. Researchers should note the importance of proper dosing to mitigate resistance development and toxicity risks. Understanding the specific interactions at the ribosomal level can guide the strategic development of novel antibiotics with reduced side effects and enhanced efficacy.Formula:C21H41N7O12•(H2SO4)1Purity:Min. 95%Molecular weight:730.71 g/molDihydrostreptomycin Sulfate
CAS:Dihydrostreptomycin and its derivatives; salts thereofFormula:(C21H41N7O12)2·3H2SO4Color and Shape:White PowderMolecular weight:1166.56264Dihydrostreptomycin Sulfate
CAS:Formula:C21H41N7O12·3H2O4SColor and Shape:White To Off-White SolidMolecular weight:2 583.60 3 98.08
