CAS 55289-06-0: 3-Methoxy-2-methylbenzoic acid

3-Methoxy-2-methylbenzoic acid is a diazotization agent that is used to produce bromoethane. It is also used as an initiator in the synthesis of dimethylformamide and tetrahydrofuran. 3-Methoxy-2-methylbenzoic acid can be recycled and is used to synthesize methylbenzene, chloroanisole, and grignard reaction products such as chlorobenzene and low yield. 3-Methoxy-2-methylbenzoic acid has been shown to have a high yield for these reactions in comparison to other diazotization agents.

3-Methoxy-2-methylbenzoic acid

Applications 3-Methoxy-2-methylbenzoic acid

3-Methoxy-2-methylbenzoic acid is used as a Corey-Bakshi-Shibata oxazaborolidine catalyst for asymmetric reduction and asymmetric synthesis. It is used in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective synthesis of α-hydroxy acids, α-amino acids, C2 symmetrical ferrocenyl diols and propargyl alcohols. It is also used in desymmetrizing reduction leading to (S)-4-hydroxycyclohexenone. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.