CAS 55715-03-2: 4-Bromomethyl-3-nitrobenzoic acid

4-Bromomethyl-3-nitro benzoic acid

4-Bromomethyl-3-nitrobenzoic acid is used as a reactant in the synthesis of 4-bromomethyl-3-nitrobenzoic acid succinimide ester, 4-((2-(hydroxymethyl)phenyl amino)methyl)-3-nitrobenzoic acid, 4-(2-hydroxyethylmercaptylmethyl)-3-nitrobenzoic acid. It is also used as a thiol photo-deprotection reagent, a starting material in the synthesis of 2H-indazole based library using parallel solution-phase methods. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

4-(Bromomethyl)-3-nitrobenzoic acid (4BMB) is a specific antibody that can be used for the treatment of cancer. 4BMB binds to the antigen CD19, which is expressed on the surface of B cells and some plasma cells. It has been shown to inhibit cell proliferation in vitro and in vivo. This drug has also been shown to have cytotoxic effects against tumor cells by inducing apoptosis. 4BMB is synthesized using a solid-phase synthesis method, and it has shown efficient binding affinity with CD19 antigen, as well as high specificity. The antibody can be successfully produced in large quantities, making it an ideal candidate for regenerative medicine.