CAS 56-05-3: 4,6-Dichloro-2-pyrimidinamine

2-Amino-4,6-dichloropyrimidine

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2-Amino-4,6-dichloropyrimidine is a chemical compound that can be used as an intermediate in the synthesis of other compounds. It is usually prepared by chlorinating 2-amino-pyrimidine with sodium hypochlorite. 2-Amino-4,6-dichloropyrimidine has been shown to inhibit the growth of herpes simplex virus and influenza virus when it is added to cell cultures. This compound also inhibits the replication of protonated nucleic acids by reacting with the amide group of nucleophilic amino acids in DNA or RNA. The reaction between 2-amino-4,6-dichloropyrimidine and amines gives pyridinium salts, which are useful intermediates in organic chemistry reactions.

Applications 2-AMINO-4,6-DICHLOROPYRIMIDINE (cas# 56-05-3) is a useful research chemical.

Microwave-assisted synthesis of pyrazolo [3, 4-d] pyrimidines from 2-amino-4, 6-dichloropyrimidine-5-carbaldehyde is under solvent-free conditions. A series of 6-alkynyl-2,4-diaminopyrimidine derivatives bearing various substituents at alkynyl moiety was prepared by the Sonogashira cross-coupling reaction of 2,4-diamino-6-iodopyrimidine using Pd(PPh3)2Cl2 as catalyst. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2-Amino-4,6-dichloropyrimidine is a chemical compound that has been used as a building block in the synthesis of other compounds. It has been shown to be useful for the preparation of 2-aminopyridine derivatives, which are used as an intermediate for research chemicals and pharmaceuticals. The compound has high purity and is available in bulk quantities.