5,6-Dihydrodeoxyuridine, with the CAS number 5626-99-3, is a nucleoside analog that is structurally related to deoxyuridine. It features a pyrimidine base, specifically uracil, which is modified by the reduction of the double bond between the 5 and 6 positions of the ring, resulting in a saturated structure. This modification can influence its biological activity, particularly in the context of DNA synthesis and repair. The compound is of interest in medicinal chemistry and virology, as it may exhibit antiviral properties and can serve as a substrate for DNA polymerases. Its solubility and stability in biological systems can vary, affecting its pharmacokinetics and potential therapeutic applications. Additionally, 5,6-dihydrodeoxyuridine can be utilized in research to study nucleic acid metabolism and the mechanisms of action of other nucleoside analogs. Overall, its unique structural characteristics make it a valuable compound for further investigation in biochemical and pharmaceutical contexts.

5,6-dihydrodeoxyuridine

5626-99-3: 2-[2-(3-nitrophenyl)ethenyl]-4-[(phenylamino)methylidene]-1,3-oxazol-5(4H)-one

5,6-Dihydro-2''-deoxyuridine

2'-Deoxy-5,6-dihydrouridine is a nucleoside analog that contains a dihydro group in its molecular structure,commonly used in base excision related studies.

2'-Deoxy-5,6-dihydrouridine

5,6-Dihydro-2'-deoxyuridine (dUrd) is a pyrimidine nucleoside that is an important component of DNA. It is phosphorylated by deoxyribonucleoside kinase to form dUrd monophosphate. This compound has been shown to inhibit the activity of catalase and other enzymes that hydrolyze hydrogen peroxide, indicating it may have antiviral properties. The enzyme activities of 5,6-dihydro-2'-deoxyuridine on simplex virus type 1 have been studied in vitro using lymphoblastoid cells. In these studies, the compounds was found to inhibit viral growth and terminate replication. 5,6-Dihydro-2'-deoxyuridine also inhibits the synthesis of DNA by inhibiting oxidative deamination reactions and termini formation in herpes simplex virus type 1. This drug has also been shown to inhibit amine oxidases in hep

CAS 5626-99-3: 5,6-dihydrodeoxyuridine

5,6-Dihydro-2''-deoxyuridine

Ref: 7W-GN1663

2'-Deoxy-5,6-dihydrouridine

Ref: TM-TNU1089

5,6-Dihydro-2'-deoxyuridine

Ref: 3D-ND07999