CAS 566-26-7: 7α-Hydroxycholesterol
Formula:C27H46O2
InChI:InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,24-,25+,26+,27-/m1/s1
InChI key:InChIKey=OYXZMSRRJOYLLO-RVOWOUOISA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=C[C@H]3O)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]
Synonyms:- (3Beta,7Alpha,8Xi)-Cholest-5-Ene-3,7-Diol
- (3β,7α)-Cholest-5-ene-3,7-diol
- 7-alpha-Hydroxycholesterol
- 7alpha -Hydroxycholesterol
- 7α-Hydroxycholest-5-en-3β-ol
- 7α-Hydroxycholesterol
- Cholest-5-Ene-3,7-Diol, (3Beta,7Alpha,8Xi)-
- Cholest-5-en-3beta,7alpha-diol
- Cholest-5-ene-3,7-diol, (3beta,7alpha)-
- Cholest-5-ene-3,7-diol, (3β,7α)-
- Cholest-5-ene-3β,7α-diol
- See more synonyms
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Found 8 products.
7a-Hydroxy Cholesterol-d7 (major)
CAS:Controlled ProductApplications Secondary metabolite of Cholesterol. A representative lot was: 84%d7; 14% d6; 1% d5 with no detectable d0. References Notaro, G., et al.: J. Nat. Prod., 55, 1588 (1992), Aydogmus, Z., et al.: Nat. Prod. Res., 18, 43 (2004), Mao, S., et al.: J. Nat. Prod ., 69, 1209 (2006), Shoji, T., et al.: J. Agric. Food Chem., 54, 884 (2006),Formula:C27H39D7O2Color and Shape:NeatMolecular weight:409.77a-Hydroxy cholesterol
CAS:Controlled Product7a-Hydroxycholesterol is a cholesterol metabolite that has been shown to inhibit the proliferation of 3T3-L1 preadipocytes and HL-60 cells. This compound also inhibits the growth of tumor cells by inhibiting the enzyme activities necessary for cell division and synthesis. 7a-Hydoxycholesterol has been found to be a potent inducer of cholesterol biosynthesis in cultured liver cells, which may be due to its ability to inhibit the conversion of cholesterol into bile acids. 7a-hydroxycholesterol has also been shown to inhibit viral replication in vitro. It binds to mitochondrial DNA and inhibits ATP production, leading to inhibition of mitochondrial membrane potential and cell death. 7a-hydroxycholesterol is also known as an oxysterol because it can be made from 25(OH)D3 or 2,5(OH)2D3. A high level of this metabolite is associated with atherosclerosis or formation of cholesterol deposits on artery wallsFormula:C27H46O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:402.65 g/mol7α-Hydroxycholesterol
CAS:7α-Hydroxycholesterol is a cholesterol oxide formed by both enzymatic and non-enzymatic oxidation. It can be used as a biomarker for lipid peroxidation.Formula:C27H46O2Purity:98.54% - 99.80%Color and Shape:SolidMolecular weight:402.657Alpha-Hydroxy Cholesterol
CAS:Controlled ProductApplications Secondary metabolite of Cholesterol. References Notaro, G., et al.: J. Nat. Prod., 55, 1588 (1992), Aydogmus, Z., et al.: Nat. Prod. Res., 18, 43 (2004), Mao, S., et al.: J. Nat. Prod ., 69, 1209 (2006), Shoji, T., et al.: J. Agric. Food Chem., 54, 884 (2006),Formula:C27H46O2Color and Shape:Off-WhiteMolecular weight:402.655-CHOLESTEN-3-β, 7-α-DIOL
CAS:Formula:C27H46O2Purity:98%Color and Shape:SolidMolecular weight:402.65293999999994
