CAS 566-28-9: 7-Ketocholesterol
Formula:C27H44O2
InChI:InChI=1S/C27H44O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-23,25,28H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,25+,26+,27-/m1/s1
InChI key:InChIKey=YIKKMWSQVKJCOP-ABXCMAEBSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3=O)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]
Synonyms:- (3Beta)-3-Hydroxycholest-5-En-7-One
- (3S,10R,13R,17R)-17-(1,5-dimethylhexyl)-3-hydroxy-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one
- (3β)-3-Hydroxycholest-5-en-7-one
- (5Beta,7Alpha)-7-Hydroxy-3-Oxocholan-24-Oic Acid
- 3-Beta-Hydroxycholest-5-En-7-One
- 3β-Hydroxy-cholest-5-ene-7-one
- 3β-Hydroxycholest-5-en-7-one
- 5-cholesten-3B-ol-7-one
- 7-Ketocholesterol
- 7-Oxocholesterol
- Cholest-5-en-3β-ol-7-one
- See more synonyms
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Found 10 products.
5-Cholesten-3β-ol-7-one
CAS:Formula:C27H44O2Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:400.647-Keto Cholesterol
CAS:Controlled ProductApplications 7-Keto Cholesterol is a metabolite of Cholesterol. References Wang, J., et al.: Biochemistry, 43, 1010 (2004), Lemaire-Ewing, S., et al.: Cell Biol. Toxicol., 21, 97 (2005), Fuda, H., et al.: J. Lipid Res., 48, 1343 ( 2007), Sasaki, H., et al.: Metabolism, 56, 357 (2007),Formula:C27H44O2Purity:~98%Color and Shape:NeatMolecular weight:400.647-Ketocholesterol
CAS:Controlled Product7-Ketocholesterol is a reactive molecule that can induce inflammation and has been shown to be associated with eye disorders. 7-Ketocholesterol is an intermediate in the biosynthesis of cholesterol and is converted to 7-keto-cholesterol by the enzyme HMG-CoA reductase. This compound has also been shown to be a potent inducer of autophagy, which is a process that degrades intracellular components. 7-Ketocholesterol binds to cell nuclei and alters their shape, which may lead to cancerous cell growth. For example, this molecule induces apoptosis in cultured human retinal pigment epithelial cells. The mechanism of action for 7-ketocholesterol involves mitochondrial membrane potential, ATP binding cassette transporters, and DNA polymerase chain reaction (PCR).Formula:C27H44O2Purity:Min. 95%Color and Shape:PowderMolecular weight:400.64 g/mol7-Ketocholesterol
CAS:7-Ketocholesterol is a metabolite of CholesterolFormula:C27H44O2Purity:97.59% - 99.46%Color and Shape:SolidMolecular weight:400.65
