
CAS 5680-51-3: cyclopropyl(3-nitrophenyl)methanone
Formula:C10H9NO3
InChI:InChI=1/C10H9NO3/c12-10(7-4-5-7)8-2-1-3-9(6-8)11(13)14/h1-3,6-7H,4-5H2
SMILES:c1cc(cc(c1)N(=O)=O)C(=O)C1CC1
Synonyms:- L3Tj Avr Cnw [Wln]
- Methanone, cyclopropyl(3-nitrophenyl)-
- Cyclopropyl(3-nitrophenyl)methanone
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cyclopropyl(3-nitrophenyl)methanone
CAS:Cyclopropyl(3-nitrophenyl)methanone is a nitro ketone that has been shown to be an effective antibacterial agent. It binds to DNA and inhibits transcription and replication, leading to cell death. Cyclopropyl(3-nitrophenyl)methanone also inhibits bacterial growth by binding to the 50S ribosomal subunit of bacteria. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Cyclopropyl(3-nitrophenyl)methanone also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g.,Formula:C10H9NO3Purity:Min. 95%Molecular weight:191.19 g/mol