4-Methyl-2(3H)-thiazolethione, also known by its CAS number 5685-06-3, is a heterocyclic compound featuring a thiazole ring, which is a five-membered ring containing both sulfur and nitrogen atoms. This compound is characterized by the presence of a methyl group at the 4-position of the thiazole ring and a thione functional group, which is a sulfur atom double-bonded to a carbon atom. It typically appears as a yellow to brown solid and is known for its distinctive odor. 4-Methyl-2(3H)-thiazolethione is utilized in various applications, including as a flavoring agent and in the synthesis of other chemical compounds. Its chemical properties include moderate solubility in organic solvents and stability under standard conditions, although it may be sensitive to strong oxidizing agents. Additionally, it exhibits biological activity, which has led to research into its potential uses in pharmaceuticals and agrochemicals. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance.

4-Methyl-2(3H)-thiazolethione

5685-06-3: 2(3H)-Thiazolethione, 4-methyl-, 2-Mercapto-4-methyl-1,3-thiazole, 2-Mercapto-4-methylthiazole, 2-Thiazolethiol, 4-methyl-, 4-Methyl-2(3H)-thiazolethione, 4-Methyl-2-mercaptothiazole, 4-Methyl-2-thiazolethiol, 4-Methyl-4-thiazoline-2-thione, 4-Methylthiazole-2-thione, 4-Methylthiazoline-2-thione, 4-Thiazoline-2-thione, 4-methyl-, 4-methyl-1,3-thiazole-2(3H)-thione, Nsc 40808

4-methylthiazole-2(3H)-thione

4-Methyl-2-thio-1,3-thiazole

4-Methylthiazole-2-thiol

4-Methyl-1,3-thiazole-2(3H)-thione is a potent inhibitor of mammalian cell growth. It has been shown to be effective against bacterial cultures, such as Staphylococcus aureus, and in vitro models of diabetic patients. 4-Methyl-1,3-thiazole-2(3H)-thione inhibits the synthesis of fatty acids by blocking the thiolation of cysteine residues. It is synthesized from 2,4-dimethylthiazolium chloride and 4-(methylsulfanyl)phenylamine. The inhibition potency values for 4-methyl-1,3-thiazole-2(3H)-thione are IC50 = 0.07 mM and IC50 = 0.03 mM on human fibroblast cells and rat liver microsomes respectively.

CAS 5685-06-3: 4-Methyl-2(3H)-thiazolethione

4-methylthiazole-2(3H)-thione

Ref: IN-DA00EJXI

4-Methyl-2-thio-1,3-thiazole

Ref: 54-OR18300

4-Methylthiazole-2-thiol

Ref: 10-F520889

4-Methyl-1,3-thiazole-2(3H)-thione

Ref: 3D-FM148856