CAS 57-04-5: Dihydroxyacetone phosphate

Glycerone phosphate lithium salt is a reactive molecule that serves as an intermediate in the synthesis of rapamycin, a complex of glycerone phosphate and rapamycin. Glycerone phosphate lithium salt is used to detect the presence of glutamate dehydrogenase and to purify monoclonal antibodies. Glycerone phosphate lithium salt has been shown to react with platinum-based chemotherapy, which may be due to its ability to bind to active sites on cancer cells. This molecule also has been shown to reduce high cholesterol levels in mice and inhibit skin cancer tumor growth. Glycerone phosphate lithium salt's physiological effects have not been fully determined, but it may have some anticancer activity.

Glycerone phosphate is a cytosolic calcium (Ca2+) substrate molecule that is used to measure the activity of phospholipase A2, an enzyme that catalyzes the hydrolysis of membrane lipids. Glycerone phosphate has been shown to inhibit neuronal death and may be useful in treating neurodegenerative diseases such as Alzheimer's disease. Glycerone phosphate has also been shown to bind to monoclonal antibodies, which are proteins that bind specifically to antigens on the surface of cancer cells, thereby preventing them from binding to their corresponding receptors on healthy cells. This may limit the spread of tumor growth and increase their sensitivity to platinum-based chemotherapy.

Dihydroxyacetone phosphate, a key in lipid synthesis and glycolysis, relates to transaldolase deficiency-a metabolic error.

Stability Hygroscopic Applications Dihydroxyacetone Phosphate Lithium Salt, is a metabolic intermediate involved in involved in a wide variety of metabolic pathways including glycolysis and lipid biosynthesis. In plants, Dihydroxyacetone phosphate is involved with the synthesis of vitamin B6. References Jun Ogawa et. al.: et al.: Bioscience, biotechnology, and biochemistry, 67(4), undefined (2003-6-6); John P Richard, Biochemistry, 51(13), undefined (2012-3-14);

Glycerone phosphate hemimagnesium salt hydrate is a substrate molecule that is used in the control analysis of dihydroxyacetone phosphate. Glycerone phosphate hemimagnesium salt hydrate is an optimum concentration for 3T3-L1 preadipocytes and has been shown to have an effect on energy metabolism. Glycerone phosphate hemimagnesium salt hydrate also has enzymatic activity, which can lead to neuronal death or skin cancer. This compound is a monosodium salt that can be found in cytosolic calcium, which is present in cells and helps regulate muscle contraction. Glycerone phosphate hemimagnesium salt hydrate can also be found in basic proteins that are vital for cell function.